Seminar on Endocrine Disrupters
Seminar on Endocrine Disrupters
5 November 2009 at 13:00 – 16:00 hrs.
Søhuset Conference Centre
Venlighedsvej 10
2970 Hørsholm, Denmark
For the last seven decades large numbers and large quantities of possibly endocrine disrupting chemicals have been released to the environment. Many of these chemicals can disturb the development of the endocrine system and the organs that respond to endocrine signals in organisms indirectly exposed during prenatal and/or early postnatal life.
Trans-generational exposure
Effects of exposure during development are often permanent and irreversible. This is seen in both environmental and mammalian studies. Trans-generational exposure can result from the exposure of the mother to a chemical at any time throughout her life before producing offspring due to persistence of endocrine disrupting chemicals in body fat, chemicals which may be mobilized during lactation.
In addition, the risk to the developing organism can also originate from direct exposure of the offspring after birth. The mechanisms underlying the disruption of the development of vital systems, such as the endocrine, reproductive, and immune systems, are many. Cocktail effects where chemicals in combination have shown to be able to potentiate each other are seen in many cases and lead to the need for new approaches when calculating the risk of chemical effects.
Programme
Time |
Subject |
Speaker |
13.00 – 13.10 |
Welcome |
Dr. Anders Permin, DHI |
13.10 – 13.40 |
The effect of endocrine disrupting substances on humans and environment |
Dr. Eric Wood, Harlan Laboratories Ltd. |
13.40 – 14.00 |
Development of in vivo guidelines for determination of endocrine disrupting effects |
Dr. Gitte Petersen, DHI |
14.00 – 14.20 |
Dr. Sofie Christiansen, The Danish National Food Institute |
|
14.20 – 14.35 |
Coffee and tea break |
|
14.35 – 14.55 |
Endocrine disrupting substances in REACH and the present EU priority list |
Gitte Petersen, DHI |
14.55 – 15.10 |
In vitro methods for determination of endocrine disrupting effects |
Ms. Tanja Krüger, Århus University |
15.10 – 15.25 |
The effect of endocrine disrupting substances on humans |
Dr. Anna-Maria Andersson, the University Hospital of Copenhagen |
15.25 – 15.45 |
Endocrine disrupting substances and the Danish and European authorities |
Marie Holmer, Danish EPA |
15.45 – 16.00 |
Summary, conclusion and discussion |
Dr. Anders Permin, DHI |